Description
Product Characteristics:
Aliases: GlnRS antibody, Glutamine tRNA ligase antibody, Glutamine tRNA synthetase antibody, Glutamine--tRNA ligase antibody, Glutaminyl tRNA ligase antibody, Glutaminyl tRNA synthetase antibody, Glutaminyl-tRNA synthetase antibody, PRO2195 antibody, QARS antibody, SYQ_HUMAN antibody
Target Information: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]